[1] 曹建,贾子才,丛培旭,等.冰岛刺参和南非花刺参脑苷脂分子种的比较[J].中国海洋大学学报(自然科学版),2016,46(9):38-44.
[2] 徐梦豪,侯召华,林荣芳,等.冰岛刺参抗癌物质Frondoside A的研究进展[J].特产研究,2020,42(5):71-77.
[3] ABUZAYTOUN R,BUDGE S,HANSEN L T,et al.Modification of the ferrous Oxidation-Xylenol orange method for determination of peroxide value in highly pigmented sea cucumber viscera lipid[J].Journal of the American Oil Chemists’ Society,2020,97(5):509-516.
[4] XU H,WANG F,WANG J F,et al.The WNT/β-catenin pathway is involved in the anti-adipogenic activity of cerebrosides from the sea cucumber Cucumaria frondosa[J].Food & Function,2015,6(7):2396-2404.
[5] JIA Z C,SONG Y,TAO S Y,et al.Structure of sphingolipids from sea cucumber Cucumaria frondosa and structure-specific cytotoxicity against human HepG2 cells[J].Lipids,2016,51(3):321-334.
[6] TIAN Y Y,HU S W,XU H,et al.Long-chain bases from Cucumaria frondosa inhibit adipogenesis and regulate lipid metabolism in 3T3-L1 adipocytes[J].Food Science & Biotechnology,2016,25(6):1753-1760.
[7] 朱启源.两种海参多糖组分的制备及其改善大鼠2型糖尿病作用研究[D].广州:华南理工大学,2020.
[8] SAJWANI F.Frondoside A is a potential anticancer agent from sea cucumbers[J].Journal of Cancer Research & Therapeutics,2019,15(5):953-960.
[9] THARINDU R L S,DEEPIKA D,FEREIDOON S.Antioxidant potential and physicochemical properties of protein hydrolysates from body parts of North Atlantic sea cucumber (Cucumaria frondosa)[J].Food Production,Processing and Nutrition,2021,3(1):3.
[10] ATTOUB S,ARAFAT K,BRACKE M,et al.Frondoside a suppressive effects on lung cancer survival,tumor growth,angiogenesis,invasion,and metastasis[J].PLoS ONE,2013,8(1):e53087.
[11] 杨坤.叶瓜参提取物的酶法制备及其抗衰老活性研究[D].广州:华南理工大学,2018.
[12] ZHANG L Y,WANG D,WEN M,et al.Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa[J].Journal of Functional Foods,2017,28:28-35.
[13] LIU X X,HAO J J,SHAN X D,et al.Antithrombotic activities of fucosylated chondroitin sulfates and their depolymerized fragments from two sea cucumbers[J].Carbohydrate Polymers,2016,152:343-350.
[14] DING L,ZHANG T T,CHE H X,et al.Saponins of sea cucumber attenuate atherosclerosis in ApoE/mice via lipid-lowering and anti-inflammatory properties[J].Journal of Functional Foods,2018,48:490-497.
[15] HU S W,WANG J H,WANG J F,et al.Long-chain bases from sea cucumber inhibits renal fibrosis and apoptosis in type 2 diabetic mice[J].Journal of Functional Foods,2018,40:760-768.
[16] 赵芹,王静凤,薛勇,等.3种海参的主要活性成分和免疫调节作用的比较研究[J].中国水产科学,2008,15(1):154-159.
[17] ZHONG Y,KHAN M A,SHAHIDI F.Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa)[J].Journal of Agricultural and Food Chemistry,2007,55(4):1188-1192.
[18] SONG Z Y,LI H L,WEN J,et al.Consumers’ attention on identification,nutritional compounds,and safety in heavy metals of Canadian sea cucumber in Chinese food market[J].Food Science & Nutrition,2020,8(11):5962-5975.
[19] USTVUZHANINA N E,BILAN M I,DMITRENOK A S,et al.The structure of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria frondosa [J].Carbohydrate Polymers,2017,165:7-12.
[20] HU S W,LI S J,SONG W D,et al.Fucoidan from Cucumaria frondosa inhibits pancreatic islets apoptosis through mitochondrial signaling pathway in insulin resistant mice[J].Food Science and Technology Research,2016,22(4):507-517.
[21] HOSSAIN A,DAVE D,SHAHIDI F.Northern sea cucumber (Cucumaria frondosa):A potential candidate for functional food,nutraceutical,and pharmaceutical sector[J].Marine Drugs,2020,18(5):274.
[22] 钟静诗,张健,刘芳,等.海参皂苷生物活性及其分子机制研究进展[J].食品与机械,2021,37(3):180-186.
,194.
[23] 董婧媛.海参皂苷的提取工艺及功能研究[D].天津:天津科技大学,2020.
[24] MOJID M M A,JAE S H,AMINUR R M,et al.Sea cucumber glycosides:Chemical structures,producing species and important biological properties[J].Marine Drugs,2017,15(10):317.
[25] XIONG Q P,SONG Z Y,HU W H,et al.Methods of extraction,separation,purification,structural characterization for polysaccharides from aquatic animals and their major pharmacological activities[J].Critical Reviews in Food Science and Nutrition,2020,60(1):48-63.
[26] CHEN F,LIN L Z,ZHAO M M,et al.Modification of Cucumaria frondosa hydrolysate through maillard reaction for sea cucumber peptide based-beverage[J].LWT-Food Science and Technology,2021,136(5):110329.
[27] 赵芹,林栋,刘海梅.冰岛刺参胶原蛋白多肽对PC12细胞氧化损伤的保护作用[J].食品工业科技,2016,37(18):354-358.
[28] 孙姿姿,徐莲,徐先锋,等.叶瓜参多肽对S180荷瘤小鼠抑瘤作用的研究[J].食品科技,2016,41(4):77-81.
[29] 徐先锋,徐莲,孙姿姿,等.冰岛刺参多肽对小鼠免疫调节功能的影响[J].食品科技,2016,41(6):67-71.
[30] LIN L Z,YANG K,ZHENG L,et al.Anti-aging effect of sea cucumber (Cucumaria frondosa) hydrolysate on fruit flies and D-galactose-induced aging mice[J].Journal of Functional Foods,2018,47:11-18.
[31] ZHONG Y,KHAN M A,SHAHIDI F.Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa) [J].Journal of Agricultural and Food Chemistiy,2007,1188-1192.
[32] MAMELONA J,PELLETIER É,LEGAULT J,et al.Quantification of phenolic contents and antioxidant capacity of Atlantic sea cucumber,Cucumaria frondosa[J].Food Chemistry,2007,104:1040-1047.
[33] NADIA A M,RABAH I,AADERRAHIM N,et al.Frondoside A inhibits human breast cancer cell survival,migration,invasion and the growth of breast tumor xenografts [J].European Journal of Pharmacology,2011,668:25-34.
[34] DU L,YANG Y H,WANG Y M,et al.Antitumour activity of EPA-enriched phospholipids liposomes against S180 ascitic tumour-bearing mice[J].Journal of Functional Foods,2015,19:970-982.
[35] STEFANIAK-VIDARSSON M M,KALE V A,MARTEINSDOTTIR G,et al.Bioactive effect of sulphated polysaccharides derived from orange-footed sea cucumber (Cucumaria frondosa) toward THP-1 macrophages[J].Bioactive Carbohydrates & Dietary Fibre,2017,12:14-19.
[36] AMININ D L,AGAFONOVA I G,KALININ V I,et al.Immunomodulatory properties of frondoside A,a major triterpene glycoside from the North Atlantic commercially harvested sea cucumber Cucumaria frondosa[J].Journal of Medicinal Food,2008,11(3):443-453.
[37] 胡世伟,王静凤,徐慧,等.冰岛刺参岩藻聚糖硫酸酯对胰岛素抵抗小鼠炎症改善作用的研究[J].中国海洋药物,2015,168(6):49-56.
[38] SANDEEP S,SANJANA C,SAEEDA A,et al.Frondanol,a nutraceutical extract from Cucumaria frondosa,attenuates colonic inflammation in a DSS-induced colitis model in mice[J].Marine Drugs,2018,16(5):148.
[39] 胡明曦,张栩,陈畅.细胞氧化还原调控与衰老[J].生物化学与生物物理进展,2014,41(3):288-294.
[40] CHEIGNON C,TOMAS M,BONNEFONT-ROUSSELOT D,et al.Oxidative stress and the amyloid beta peptide in Alzheimer’s disease[J].Redox Biol,2018,14:450-464.
[41] WANG C C,WANG D,ZHANG T T,et al.A comparative study about EPA-PL and EPA-EE on ameliorating behavioral deficits in MPTP-induced mice with Parkinson’s disease by suppressing oxidative stress and apoptosis[J].Journal of Functional Foods,2018,50:8-17.
[42] 荣怡,董笑晨,张国鹏,等.北京居民对于高血压、高血脂和高血糖的认知与消费现状研究[J].现代食品,2018(24):182-189.
[43] HU S W,XU L L,SHI D,et al.Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway[J].Journal of Bioscience & Bioengineering,2014,117(4):457-463.
[44] ZHU Q Y,LIN L Z,ZHAO M M.Sulfated fucan/fucosylated chondroitin sulfate-dominated polysaccharide fraction from low-edible-value sea cucumber ameliorates type 2 diabetes in rats:New prospects for sea cucumber polysaccharide based-hypoglycemic functional food[J].International Journal of Biological Macromolecules,2020,159:34-45.
[45] WANG Y M,WANG J F,ZHAO Y L,et al.Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4[J].Journal of Bioence & Bioengineering,2016,121(1):36-42.
[46] DUAN X, ZHANG M, MUJUMDAR A S.Study on a combination drying technique of sea cucumber[J].Drying Technology,2007,25(12):2011-2019.