WANG Pei-yuan, KANG Hua-kui, SUN Shu-min and et al. Study on synthesis of amino functionalized organic-inorganic hybrid mesoporous materials and drug delivery property[J]. Journal of Light Industry, 2013, 28(4): 1-5. doi: 10.3969/j.issn.2095-476X.2013.04.001
Citation:
WANG Pei-yuan, KANG Hua-kui, SUN Shu-min and et al. Study on synthesis of amino functionalized organic-inorganic hybrid mesoporous materials and drug delivery property[J]. Journal of Light Industry, 2013, 28(4): 1-5.
doi:
10.3969/j.issn.2095-476X.2013.04.001
Study on synthesis of amino functionalized organic-inorganic hybrid mesoporous materials and drug delivery property
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College of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China;
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He'nan Provincial Key Labortory of Surface and Interface Science, Zhengzhou University of Light Industry, Zhengzhou 450001, China
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Corresponding author:
FANG Shao-ming,
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Received Date:
2013-03-08
Available Online:
2013-07-15
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Abstract
Amino group-functionalized mesoporous ethane-silicas were synthesized by co-condensation of 1,2-bis(trimethoxysily)ethane (BTME) and 3-aminopropyltriethoxysilane(AMPTS).TEM,XRD,nitrogen adsorption and desorption,FT-IR,elemental analysis and 13C NMR were used to characterize the obtained materials.Ibuprofen was used as a model drug to test the drug adsorption and release properties of mesoporous materials.The results showed that amino group-functionalized mesoporous ethane-silicas presented stronger adsorption capacity,which could increase up to 0.78 g/g from 0.35 g/g.Compared with EA-0,the materials EA-20 had a better sustained release effect during the release process.
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Proportional views
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