调节血清胆固醇的保健功能食品研究综述
Review of health functional foods for serum cholesterol-regulating
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摘要: 从分析我国近年膳食转型与心血管疾病高发的关联入手,综述了造成血清胆固醇升高的主要因素,以及调节血清胆固醇的天然活性成分及保健功能食品:造成血清胆固醇升高的主要膳食特征为高脂、高热量、低纤维、低碳水化合物;调节血清胆固醇的天然活性成分有HMG-CoA还原酶抑制剂、LDL受体激活剂、NPC1L1抑制剂、Intestinal ACAT抑制剂、胆汁酸再吸收抑制剂、CETP抑制剂;能够调节血清胆固醇含量的保健功能食品有膳食纤维、山楂黄酮、苹果多酚以及荞麦面粉等.Abstract: Starting from the analysis of the current Chinese dietary transition problem and the relationship with high incidence of the diseasecardiovascular disease,the main factors causing increase in serum cholesterol levels and the cholesterol-regulating nutraceuticals and functional foods was reviewed.The diet characteristics resulted in the increase of serum cholesterol were high-fat,high-calorie,low-carbohydrate and low fiber compounds.The natural compounds for serum cholesterol regulation were HMG-CoA reductase inhibitors,LDL receptor activators,NPC1L1 competitors,intestinal ACAT inhibitors,bile acid re-absorption inhibitor/bile acid binding resin and CETP inhibitors.The cholesterol-regulating functional foods included dietary fibers,hawthorn flavonoids,apple polyphenols,buck wheat,etc.
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Key words:
- serum cholesterol /
- cardiovascular disease /
- dietary transition /
- nutraceutical /
- functional food
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