JOURNAL OF LIGHT INDUSTRY

CN 41-1437/TS  ISSN 2096-1553

调节血清胆固醇的保健功能食品研究综述

许春平 ,  杨琛琛

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许春平, 杨琛琛. 调节血清胆固醇的保健功能食品研究综述[J]. 轻工学报, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
引用本文: 许春平, 杨琛琛. 调节血清胆固醇的保健功能食品研究综述[J]. 轻工学报, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
shu
XU Chun-ping and YANG Chen-chen. Review of health functional foods for serum cholesterol-regulating[J]. Journal of Light Industry, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
Citation: XU Chun-ping and YANG Chen-chen. Review of health functional foods for serum cholesterol-regulating[J]. Journal of Light Industry, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
shu

调节血清胆固醇的保健功能食品研究综述

  • 郑州轻工业学院 食品与生物工程学院, 河南 郑州 450001

  • 中图分类号: TS218

Review of health functional foods for serum cholesterol-regulating

  • College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China

  • Received Date: 2013-10-18
    Available Online: 2014-01-15

    CLC number: TS218

  • 摘要: 从分析我国近年膳食转型与心血管疾病高发的关联入手,综述了造成血清胆固醇升高的主要因素,以及调节血清胆固醇的天然活性成分及保健功能食品:造成血清胆固醇升高的主要膳食特征为高脂、高热量、低纤维、低碳水化合物;调节血清胆固醇的天然活性成分有HMG-CoA还原酶抑制剂、LDL受体激活剂、NPC1L1抑制剂、Intestinal ACAT抑制剂、胆汁酸再吸收抑制剂、CETP抑制剂;能够调节血清胆固醇含量的保健功能食品有膳食纤维、山楂黄酮、苹果多酚以及荞麦面粉等.
    Abstract: Starting from the analysis of the current Chinese dietary transition problem and the relationship with high incidence of the diseasecardiovascular disease,the main factors causing increase in serum cholesterol levels and the cholesterol-regulating nutraceuticals and functional foods was reviewed.The diet characteristics resulted in the increase of serum cholesterol were high-fat,high-calorie,low-carbohydrate and low fiber compounds.The natural compounds for serum cholesterol regulation were HMG-CoA reductase inhibitors,LDL receptor activators,NPC1L1 competitors,intestinal ACAT inhibitors,bile acid re-absorption inhibitor/bile acid binding resin and CETP inhibitors.The cholesterol-regulating functional foods included dietary fibers,hawthorn flavonoids,apple polyphenols,buck wheat,etc.
    1. [1]

      世界卫生组织.世卫组织提醒全球有效控制高胆固醇[J].生物学通报,2011,46(3):55.

    2. [2]

      赵峥,倪鹏飞.当前我国城镇化发展的特征、问题及政策建议[J].中国国情国力,2012 (2):10.

    3. [3]

      李立明,饶克勤,孔灵芝,等.中国居民2002年营养与健康状况调查[J].中华流行病学杂志,2005,26(7):478.

    4. [4]

      翟凤英,王惠君,王志宏,等.中国居民膳食营养状况的变迁及政策建议[J].中国食物与营养,2006(5):4.

    5. [5]

      Steinberg D.An interpretive history of the cholesterol controversy(part V):The discovery of the statins and the end of the controversy[J].J Lipid Res,2005,46:179.

    6. [6]

      Li Z,Yang R,Xu G,et al.Serum lipid concentrations and prevalence of dyslipidemia in a large professional population in Beijing[J].Clin Chem,2005,51:144.

    7. [7]

      Jung K,Song C,Barrett-Conno E.Association of reported nighttime sleep and daytime nap with 19-year mortality in older adults[J].European Neuropsychopharmacology,2009,19(3):334.

    8. [8]

      Keys A.Atherosclerosis:A problem in newer public health[J].J Mt Sinai Hosp,1953(20):118.

    9. [9]

      Ng C H,Yao X Q,Huang Y,et al.Oxidised cholesterol is more hypercholesterolaemic and atherogenic than non-oxidised cholesterol in hamsters[J].Br J Nutr,2008,99:749.

    10. [10]

      Hu F B,Manson J E,Willett W C.Types of dietary fat and risk of coronary heart disease:A critical review[J].J Am Coll Nutr,2001,20:5.

    11. [11]

      Kromhout D,Menotti A,Bloemberg B,et al.Dietary saturated and transfatty acids and cholesterol and 25-year mortality from coronary heart disease:The seven countries study[J].Preventive Medicine,1995,24:308.

    12. [12]

      Chen Z Y,Jiao R,Ma K Y,et al.Cholesterol-lowering nutraceuticals and functional food[J].J Agric Food Chem,2008,56:8761.

    13. [13]

      Pereira M A,O'Reilly E,Augustsson K,et al.Dietary fiber and risk of coronary heart disease:A pooled analysis of cohort studies[J].Arch Intern Med,2004,164:370.

    14. [14]

      Brown L,Rosner B,Willett W W,et al.Cholesterol-lowering effects of dietary fiber:A meta-analysis[J].Am J Clin Nutr,1999,69:30.

    15. [15]

      Naumann E,Van Rees A B,Onning G,et al.Beta-glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations[J].Am J Clin Nutr,2006,83:601.

    16. [16]

      Chen J T,Wesley R,Shamburek R D,et al.Meta-analysis of natural therapies for hyperlipidemia:Plant sterols and stanols versus policosanol[J].Pharmacotherapy,2005,25:171.

    17. [17]

      Chen J N,Jiang Y,Ma K Y,et al.Microalgae decreases plasma cholesterol by down-regulation of intestinal NPC1L1,hepatic LDL receptor and HMG-CoA reductase[J].Journal of Agricultural and Food Chemistry,2011,59:6790.

    18. [18]

      Mellen P B,Walsh T F,Herrington D M.Whole grain intake and cardiovascular disease:A meta-analysis[J].Nutr Metab Cardiovas Dis,2008,18:283.

    19. [19]

      Chan P T,Fong W P,Cheung Y L,et al.Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet[J].J Nutr,1999,129:1094.

    20. [20]

      Guan L,Yeung S Y,Huang Y,et al.Both soybean and kudzu phytoestrogens modify favorably the blood lipoprotein profile in ovariectomized and castrated hamsters[J].J Agric Food Chem 2006,54:4907.

    21. [21]

      Bursill C A,Roach P D.A green tea catechin extract upregulates the hepatic low-density lipoprotein receptor in rats[J].Atherosclerosis,2007,193:86.

    22. [22]

      Zhang Z,Ho W K,Huang Y,et al.Hawthorn fruit is hypolipidemic in rabbits fed a high cholesterol diet[J].J Nutr,2002,132:5.

    23. [23]

      Chiu C H,Lu T Y,Tseng Y Y,et al.The effects of Lactobacillus-fermented milk on lipid metabolism in hamsters fed on high-cholesterol diet[J].Appl Microbiol and Technol,2006,71:238.

    24. [24]

      Yeh Y Y,Liu L.Cholesterol-lowering effect of garlic extracts and organosulfur compounds:Human and animal studies[J].J Nutr,2001,131:989S.

    25. [25]

      Ng C H,Leung K Y,Huang Y.et al.Policosanol has no antioxidant activity in human low-density lipoprotein but increases excretion of bile acids in hamsters[J].J Agric Food Chem,2005,53:6289.

    26. [26]

      Lam C K,Zhang Z,Yu H,et al.Apple polyphenols inhibit plasma CETP activity and reduce the ratio of non-HDL to HDL cholesterol[J].Mol Nutr Food Res,2008,52:950.

    27. [27]

      Jiao R,Zhang Z,Yu H,et al.Hypocholesterolemic activity of grape seed proanthocyanidin is mediated by enhancement of bile acid excretion and up-regulation of CYP7A1[J].Journal of Nutritional Biochemistry,2010,21:1134.

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  • 收稿日期:  2013-10-18
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许春平, 杨琛琛. 调节血清胆固醇的保健功能食品研究综述[J]. 轻工学报, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
引用本文: 许春平, 杨琛琛. 调节血清胆固醇的保健功能食品研究综述[J]. 轻工学报, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
shu
XU Chun-ping and YANG Chen-chen. Review of health functional foods for serum cholesterol-regulating[J]. Journal of Light Industry, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
Citation: XU Chun-ping and YANG Chen-chen. Review of health functional foods for serum cholesterol-regulating[J]. Journal of Light Industry, 2014, 29(1): 44-47. doi: 10.3969/j.issn.2095-476X.2014.01.008
shu

调节血清胆固醇的保健功能食品研究综述

  • 郑州轻工业学院 食品与生物工程学院, 河南 郑州 450001
  • 收稿日期: 2013-10-18
  • 网络出版日期: 2014-01-15

摘要: 从分析我国近年膳食转型与心血管疾病高发的关联入手,综述了造成血清胆固醇升高的主要因素,以及调节血清胆固醇的天然活性成分及保健功能食品:造成血清胆固醇升高的主要膳食特征为高脂、高热量、低纤维、低碳水化合物;调节血清胆固醇的天然活性成分有HMG-CoA还原酶抑制剂、LDL受体激活剂、NPC1L1抑制剂、Intestinal ACAT抑制剂、胆汁酸再吸收抑制剂、CETP抑制剂;能够调节血清胆固醇含量的保健功能食品有膳食纤维、山楂黄酮、苹果多酚以及荞麦面粉等.

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