JOURNAL OF LIGHT INDUSTRY

CN 41-1437/TS  ISSN 2096-1553

冰岛刺参生物活性成分及其功能活性研究进展

赵祥忠 ,  高云龙 ,  徐梦豪 ,  朱纪海

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赵祥忠, 高云龙, 徐梦豪, 等. 冰岛刺参生物活性成分及其功能活性研究进展[J]. 轻工学报, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
引用本文: 赵祥忠, 高云龙, 徐梦豪, 等. 冰岛刺参生物活性成分及其功能活性研究进展[J]. 轻工学报, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
shu
ZHAO Xiangzhong, GAO Yunlong, XU Menghao and et al. Research progress on bioactive components and their functional activities of Cucumaria frondosa[J]. Journal of Light Industry, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
Citation: ZHAO Xiangzhong, GAO Yunlong, XU Menghao and et al. Research progress on bioactive components and their functional activities of Cucumaria frondosa[J]. Journal of Light Industry, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
shu

冰岛刺参生物活性成分及其功能活性研究进展

  • 1. 齐鲁工业大学(山东省科学院) 食品科学与工程学院, 山东 济南 250353;

  • 2. 山东中硕海洋科技有限公司, 山东 日照 276800

    • 作者简介: 赵祥忠(1969—),男,山东省潍坊市人,齐鲁工业大学副教授,主要研究方向为海洋食品与生物技术。E-mail:13506416163@163.com;

  • 基金项目: 山东省自然科学基金项目(ZR2020QC221)

  • 中图分类号: TS254.5

Research progress on bioactive components and their functional activities of Cucumaria frondosa

  • 1. School of Food Science and Engineering, Qilu University of Technology (Shandong Academy of Science), Jinan 250353, China;

  • 2. Shandong Zhongshuo Marine Technology Co., Ltd., Rizhao 276800, China

  • Received Date: 2021-03-30
    Accepted Date: 2022-09-14

    CLC number: TS254.5

  • 摘要: 对冰岛刺参生物活性成分的组成、功能活性等研究进行综述,指出,冰岛刺参含有脂类、多糖类、皂苷类、多肽及蛋白质类等多种生物活性成分,具有抗肿瘤、免疫调节、抗炎、抗衰老等功能活性,在功能性食品、营养保健品等方面具有潜在用途。未来可创新冰岛刺参深加工技术,加强冰岛刺参活性成分的功能活性、药理效力研究,提高内脏等副产物的附加值,以期为冰岛刺参的高值化利用和全产业链开发提供参考。
    Abstract: The composition, fuctional activities of bioactive components of Cucumaria frondosa were reviewed, It was pointed out that Cucumaria frondosa contained a variety of bioactive components such as lipids, polysaccharides, saponins and peptides. They had functional activities such as antitumor, immune regulation, anti-inflammatory and anti-aging. They had potential applications in functional food and nutritional health products. In the future, we could innovate the deep-processing technology of Cucumaria frondosa, strengthen the research on the functional activities and pharmacological effect of the bioactive components of Cucumaria frondosa, increase the added value of visceral and other by-products, so as to provide reference for the high-value utilization and the development of the whole industrial chain of Cucumaria frondosa.
    1. [1]

      曹建,贾子才,丛培旭,等.冰岛刺参和南非花刺参脑苷脂分子种的比较[J].中国海洋大学学报(自然科学版),2016,46(9):38-44.

    2. [2]

      徐梦豪,侯召华,林荣芳,等.冰岛刺参抗癌物质Frondoside A的研究进展[J].特产研究,2020,42(5):71-77.

    3. [3]

      ABUZAYTOUN R,BUDGE S,HANSEN L T,et al.Modification of the ferrous Oxidation-Xylenol orange method for determination of peroxide value in highly pigmented sea cucumber viscera lipid[J].Journal of the American Oil Chemists’ Society,2020,97(5):509-516.

    4. [4]

      XU H,WANG F,WANG J F,et al.The WNT/β-catenin pathway is involved in the anti-adipogenic activity of cerebrosides from the sea cucumber Cucumaria frondosa[J].Food & Function,2015,6(7):2396-2404.

    5. [5]

      JIA Z C,SONG Y,TAO S Y,et al.Structure of sphingolipids from sea cucumber Cucumaria frondosa and structure-specific cytotoxicity against human HepG2 cells[J].Lipids,2016,51(3):321-334.

    6. [6]

      TIAN Y Y,HU S W,XU H,et al.Long-chain bases from Cucumaria frondosa inhibit adipogenesis and regulate lipid metabolism in 3T3-L1 adipocytes[J].Food Science & Biotechnology,2016,25(6):1753-1760.

    7. [7]

      朱启源.两种海参多糖组分的制备及其改善大鼠2型糖尿病作用研究[D].广州:华南理工大学,2020.

    8. [8]

      SAJWANI F.Frondoside A is a potential anticancer agent from sea cucumbers[J].Journal of Cancer Research & Therapeutics,2019,15(5):953-960.

    9. [9]

      THARINDU R L S,DEEPIKA D,FEREIDOON S.Antioxidant potential and physicochemical properties of protein hydrolysates from body parts of North Atlantic sea cucumber (Cucumaria frondosa)[J].Food Production,Processing and Nutrition,2021,3(1):3.

    10. [10]

      ATTOUB S,ARAFAT K,BRACKE M,et al.Frondoside a suppressive effects on lung cancer survival,tumor growth,angiogenesis,invasion,and metastasis[J].PLoS ONE,2013,8(1):e53087.

    11. [11]

      杨坤.叶瓜参提取物的酶法制备及其抗衰老活性研究[D].广州:华南理工大学,2018.

    12. [12]

      ZHANG L Y,WANG D,WEN M,et al.Rapid modulation of lipid metabolism in C57BL/6J mice induced by eicosapentaenoic acid-enriched phospholipid from Cucumaria frondosa[J].Journal of Functional Foods,2017,28:28-35.

    13. [13]

      LIU X X,HAO J J,SHAN X D,et al.Antithrombotic activities of fucosylated chondroitin sulfates and their depolymerized fragments from two sea cucumbers[J].Carbohydrate Polymers,2016,152:343-350.

    14. [14]

      DING L,ZHANG T T,CHE H X,et al.Saponins of sea cucumber attenuate atherosclerosis in ApoE/mice via lipid-lowering and anti-inflammatory properties[J].Journal of Functional Foods,2018,48:490-497.

    15. [15]

      HU S W,WANG J H,WANG J F,et al.Long-chain bases from sea cucumber inhibits renal fibrosis and apoptosis in type 2 diabetic mice[J].Journal of Functional Foods,2018,40:760-768.

    16. [16]

      赵芹,王静凤,薛勇,等.3种海参的主要活性成分和免疫调节作用的比较研究[J].中国水产科学,2008,15(1):154-159.

    17. [17]

      ZHONG Y,KHAN M A,SHAHIDI F.Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa)[J].Journal of Agricultural and Food Chemistry,2007,55(4):1188-1192.

    18. [18]

      SONG Z Y,LI H L,WEN J,et al.Consumers’ attention on identification,nutritional compounds,and safety in heavy metals of Canadian sea cucumber in Chinese food market[J].Food Science & Nutrition,2020,8(11):5962-5975.

    19. [19]

      USTVUZHANINA N E,BILAN M I,DMITRENOK A S,et al.The structure of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria frondosa [J].Carbohydrate Polymers,2017,165:7-12.

    20. [20]

      HU S W,LI S J,SONG W D,et al.Fucoidan from Cucumaria frondosa inhibits pancreatic islets apoptosis through mitochondrial signaling pathway in insulin resistant mice[J].Food Science and Technology Research,2016,22(4):507-517.

    21. [21]

      HOSSAIN A,DAVE D,SHAHIDI F.Northern sea cucumber (Cucumaria frondosa):A potential candidate for functional food,nutraceutical,and pharmaceutical sector[J].Marine Drugs,2020,18(5):274.

    22. [22]

      钟静诗,张健,刘芳,等.海参皂苷生物活性及其分子机制研究进展[J].食品与机械,2021,37(3):180-186
      ,194.

    23. [23]

      董婧媛.海参皂苷的提取工艺及功能研究[D].天津:天津科技大学,2020.

    24. [24]

      MOJID M M A,JAE S H,AMINUR R M,et al.Sea cucumber glycosides:Chemical structures,producing species and important biological properties[J].Marine Drugs,2017,15(10):317.

    25. [25]

      XIONG Q P,SONG Z Y,HU W H,et al.Methods of extraction,separation,purification,structural characterization for polysaccharides from aquatic animals and their major pharmacological activities[J].Critical Reviews in Food Science and Nutrition,2020,60(1):48-63.

    26. [26]

      CHEN F,LIN L Z,ZHAO M M,et al.Modification of Cucumaria frondosa hydrolysate through maillard reaction for sea cucumber peptide based-beverage[J].LWT-Food Science and Technology,2021,136(5):110329.

    27. [27]

      赵芹,林栋,刘海梅.冰岛刺参胶原蛋白多肽对PC12细胞氧化损伤的保护作用[J].食品工业科技,2016,37(18):354-358.

    28. [28]

      孙姿姿,徐莲,徐先锋,等.叶瓜参多肽对S180荷瘤小鼠抑瘤作用的研究[J].食品科技,2016,41(4):77-81.

    29. [29]

      徐先锋,徐莲,孙姿姿,等.冰岛刺参多肽对小鼠免疫调节功能的影响[J].食品科技,2016,41(6):67-71.

    30. [30]

      LIN L Z,YANG K,ZHENG L,et al.Anti-aging effect of sea cucumber (Cucumaria frondosa) hydrolysate on fruit flies and D-galactose-induced aging mice[J].Journal of Functional Foods,2018,47:11-18.

    31. [31]

      ZHONG Y,KHAN M A,SHAHIDI F.Compositional characteristics and antioxidant properties of fresh and processed sea cucumber (Cucumaria frondosa) [J].Journal of Agricultural and Food Chemistiy,2007,1188-1192.

    32. [32]

      MAMELONA J,PELLETIER É,LEGAULT J,et al.Quantification of phenolic contents and antioxidant capacity of Atlantic sea cucumber,Cucumaria frondosa[J].Food Chemistry,2007,104:1040-1047.

    33. [33]

      NADIA A M,RABAH I,AADERRAHIM N,et al.Frondoside A inhibits human breast cancer cell survival,migration,invasion and the growth of breast tumor xenografts [J].European Journal of Pharmacology,2011,668:25-34.

    34. [34]

      DU L,YANG Y H,WANG Y M,et al.Antitumour activity of EPA-enriched phospholipids liposomes against S180 ascitic tumour-bearing mice[J].Journal of Functional Foods,2015,19:970-982.

    35. [35]

      STEFANIAK-VIDARSSON M M,KALE V A,MARTEINSDOTTIR G,et al.Bioactive effect of sulphated polysaccharides derived from orange-footed sea cucumber (Cucumaria frondosa) toward THP-1 macrophages[J].Bioactive Carbohydrates & Dietary Fibre,2017,12:14-19.

    36. [36]

      AMININ D L,AGAFONOVA I G,KALININ V I,et al.Immunomodulatory properties of frondoside A,a major triterpene glycoside from the North Atlantic commercially harvested sea cucumber Cucumaria frondosa[J].Journal of Medicinal Food,2008,11(3):443-453.

    37. [37]

      胡世伟,王静凤,徐慧,等.冰岛刺参岩藻聚糖硫酸酯对胰岛素抵抗小鼠炎症改善作用的研究[J].中国海洋药物,2015,168(6):49-56.

    38. [38]

      SANDEEP S,SANJANA C,SAEEDA A,et al.Frondanol,a nutraceutical extract from Cucumaria frondosa,attenuates colonic inflammation in a DSS-induced colitis model in mice[J].Marine Drugs,2018,16(5):148.

    39. [39]

      胡明曦,张栩,陈畅.细胞氧化还原调控与衰老[J].生物化学与生物物理进展,2014,41(3):288-294.

    40. [40]

      CHEIGNON C,TOMAS M,BONNEFONT-ROUSSELOT D,et al.Oxidative stress and the amyloid beta peptide in Alzheimer’s disease[J].Redox Biol,2018,14:450-464.

    41. [41]

      WANG C C,WANG D,ZHANG T T,et al.A comparative study about EPA-PL and EPA-EE on ameliorating behavioral deficits in MPTP-induced mice with Parkinson’s disease by suppressing oxidative stress and apoptosis[J].Journal of Functional Foods,2018,50:8-17.

    42. [42]

      荣怡,董笑晨,张国鹏,等.北京居民对于高血压、高血脂和高血糖的认知与消费现状研究[J].现代食品,2018(24):182-189.

    43. [43]

      HU S W,XU L L,SHI D,et al.Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway[J].Journal of Bioscience & Bioengineering,2014,117(4):457-463.

    44. [44]

      ZHU Q Y,LIN L Z,ZHAO M M.Sulfated fucan/fucosylated chondroitin sulfate-dominated polysaccharide fraction from low-edible-value sea cucumber ameliorates type 2 diabetes in rats:New prospects for sea cucumber polysaccharide based-hypoglycemic functional food[J].International Journal of Biological Macromolecules,2020,159:34-45.

    45. [45]

      WANG Y M,WANG J F,ZHAO Y L,et al.Fucoidan from sea cucumber Cucumaria frondosa exhibits anti-hyperglycemic effects in insulin resistant mice via activating the PI3K/PKB pathway and GLUT4[J].Journal of Bioence & Bioengineering,2016,121(1):36-42.

    46. [46]

      DUAN X, ZHANG M, MUJUMDAR A S.Study on a combination drying technique of sea cucumber[J].Drying Technology,2007,25(12):2011-2019.

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  • 收稿日期:  2021-03-30
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赵祥忠, 高云龙, 徐梦豪, 等. 冰岛刺参生物活性成分及其功能活性研究进展[J]. 轻工学报, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
引用本文: 赵祥忠, 高云龙, 徐梦豪, 等. 冰岛刺参生物活性成分及其功能活性研究进展[J]. 轻工学报, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
shu
ZHAO Xiangzhong, GAO Yunlong, XU Menghao and et al. Research progress on bioactive components and their functional activities of Cucumaria frondosa[J]. Journal of Light Industry, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
Citation: ZHAO Xiangzhong, GAO Yunlong, XU Menghao and et al. Research progress on bioactive components and their functional activities of Cucumaria frondosa[J]. Journal of Light Industry, 2022, 37(6): 11-17. doi: 10.12187/2022.06.002
shu

冰岛刺参生物活性成分及其功能活性研究进展

    作者简介:赵祥忠(1969—),男,山东省潍坊市人,齐鲁工业大学副教授,主要研究方向为海洋食品与生物技术。E-mail:13506416163@163.com
  • 1. 齐鲁工业大学(山东省科学院) 食品科学与工程学院, 山东 济南 250353;
  • 2. 山东中硕海洋科技有限公司, 山东 日照 276800
  • 收稿日期: 2021-03-30
  • 录用日期: 2022-09-14
基金项目:  山东省自然科学基金项目(ZR2020QC221)

摘要: 对冰岛刺参生物活性成分的组成、功能活性等研究进行综述,指出,冰岛刺参含有脂类、多糖类、皂苷类、多肽及蛋白质类等多种生物活性成分,具有抗肿瘤、免疫调节、抗炎、抗衰老等功能活性,在功能性食品、营养保健品等方面具有潜在用途。未来可创新冰岛刺参深加工技术,加强冰岛刺参活性成分的功能活性、药理效力研究,提高内脏等副产物的附加值,以期为冰岛刺参的高值化利用和全产业链开发提供参考。

English Abstract

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