ZHANG Gai-hong, LIU Yu, LI Xue-long, et al. Study on synthesis of α-ionol-β-D-glucoside by phrase transfer catalytic method[J]. Journal of Light Industry, 2017, 32(4): 43-48. doi: 10.3969/j.issn.2096-1553.2017.4.007
Citation:
ZHANG Gai-hong, LIU Yu, LI Xue-long, et al. Study on synthesis of α-ionol-β-D-glucoside by phrase transfer catalytic method[J]. Journal of Light Industry, 2017, 32(4): 43-48.
doi:
10.3969/j.issn.2096-1553.2017.4.007
Study on synthesis of α-ionol-β-D-glucoside by phrase transfer catalytic method
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Received Date:
2016-06-08
Accepted Date:
2016-12-28
Available Online:
2017-07-15
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Abstract
α-ionol was synthesized from α-ionone via the selective reduction.α-ionol-β-D-glucoside was synthesized from α-ionol via the reaction with tetra-O-α-acetyl-D-glucopyranosyl bromide under the phase transfer catalyst to give the corresponding α-ionol-2,3,4,6-tetra-O-acetyl-β-D-glucoside,followed by deacetylation.The appropriate conditions for this glucosidation reaction were as follows:10% tetrabutyl ammonium bromide was added to catalyze a reaction between Br-glucose-tetraacetateand α-ionol at a ratio of 1.6:1 in CHCl3-H2O allowed to proceed for 8 h at 60 ℃.The yield rate of glycosylation reaction was 30%.The target products were characterized β-configuration by FT-IR,1H NMR and ESI-MS.
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Proportional views
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