明胶/聚甲基丙烯酸复合水凝胶的制备及其性能研究
Study on preparation and properties of gelatin/polymethacrylic acid composite hydrogel
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摘要: 以天然高分子明胶、甲基丙烯酸（MAA）为原料，以过硫酸铵（APS）为引发剂，通过自由基聚合法制备了明胶/聚甲基丙烯酸（明胶/PMAA）复合水凝胶，并研究了不同组分质量比对该复合水凝胶导电性能、流变性能、力学性能等的影响.结果表明：随着MAA用量的增加，复合水凝胶的电导率可增至6.52×10-3 S/cm，且其电导率随其形变不同而发生变化，具有良好的机械应变响应能力；当m（明胶）：m（MAA）=12：10时，复合水凝胶G12PA10的流变性能和力学性能最好，其储能模量G'约为18.0 kPa，拉伸强度为77.3 kPa，断裂伸长率为340%，压缩模量为2.37 MPa；随着MAA用量的增大，明胶/PMAA复合水凝胶在去离子水中的溶胀平衡时间、溶胀平衡率变化趋势与在PBS缓冲液中基本一致，但当MAA用量较低时，明胶/PMAA复合水凝胶在PBS缓冲液中的溶胀平衡率略有增大.
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关键词:
- 明胶/聚甲基丙烯酸复合水凝胶 /
- 自由基聚合法 /
- 导电性能 /
- 流变性能 /
- 力学性能
Abstract: Using nature polymer gelatin and methacrylic acid (MAA) as raw materials,and ammonium persulfate (APS) as an initiator,a gelatin/polymethacrylic acid (gelatin/PMAA) composite hydrogel was synthesized via free radical polymerization.The effects of different component mass ratios on the conductive properties,rheological properties and mechanical properties of the composite hydrogel were studied.The results showed that the conductivity of the composite hydrogels adjusted to 6.52×10-3 S/cm with the dosage of MAA increasing.The conductivity also varied with the deformation of the hydrogel,making gelatin/PMAA composite hydrogel in terms of strain sensor have great potential applications.When the gelatin/PMAA composite hydrogel contained gelatin of 12% and MAA of 10%,named G12PA10,it exhibited optimal rheological properties and mechanical properties:storage modulus G' was up to 18.0 kPa,elongation at break was 340%,and compression modulus was 2.37 MPa.As the dosage of MAA increased,the swelling equilibrium time and swelling equilibrium rate of the gelatin/PMAA composite hydrogel in deionized water were basically the same as those in PBS buffer.But when the dosage of MAA was lower,the swelling equilibrium rate of gelatin/PMAA composite hydrogel in PBS solution increased slightly. -
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[1]
THAKUR S,GOVENDER P P,MAMO M A,et al.Recent progress in gelatin hydrogel nanocomposites for water purification and beyond[J].Vacuum,2017,146:396.
-
[2]
PAN Y,GAO Y,SHI J F,et al.A versatile supra-molecular hydrogel of nitrilotriacetic acid (NTA) for binding metal ions and magnetorheological response[J].Journal of Materials Chemistry,2011,21(19):6804.
-
[3]
CHENG Y,REN K,YANG D,et al.Bilayer-type fluorescence hydrogels with intelligent response serve as temperature/pH driven soft actuators[J].Sensors and Actuators B:Chemical,2017,255:3117.
-
[4]
HUANG C,CHENG Y,GAO Z,et al.Portable label-free inverse opal photonic hydrogel particles serve as facile pesticides colorimetric monitoring[J].Sensors and Actuators B(Chemical),2018,273:1705.
-
[5]
CHENG Y,HUANG C,YANG D,et al.Bilayer hydrogel mixed composites that respond to multiple stimuli for environmental sensing and underwater actuation[J].Journal of Materials Chemistry B,2018,6:8170.
-
[6]
LIU Y J,CAO W T,MA M G,et al.Ultrasensitive wearable soft strain sensors of conductive,self-healing,and elastic hydrogels with synergistic "soft and hard" hybrid networks[J].ACS Applied Materials & Interfaces,2017,9(30):25559.
-
[7]
SATARKAR N S,HILT J Z.Magnetic hydrogel nanocomposites for remote controlled pulsatile drug release[J].Journal of Controlled Release,2008,130(3):246.
-
[8]
PISSIS P,KYRITSIS A.Electrical conductivity studies in hydrogels[J].Solid State Ionics,1997,97(1/2/3/4):105.
-
[9]
BALINT R,CASSIDY N J,CARTMELL S H.Conductive polymers:Towards a smart biomaterial for tissue engineering[J].Acta Biomaterialia,2014,10(6):2341.
-
[10]
XIA Y Y,ZHU H L.Polyaniline nanofiber-reinforced conducting hydrogel with unique pH-sensitivity[J].Soft Matter,2011,7(19):9388.
-
[11]
YAPICI M K,TAMADOR A,SAMAD Y A,et al.Graphene-clad textile electrodes for electrocardiogram monitoring[J].Sensors and Actuators B(Chemical),2015,221:1469.
-
[12]
CHEN Z,TO J W F,WANG C,et al.A three-dimensionally interconnected carbon nanotube-conducting polymer hydrogel network for high-performance flexible battery electrodes[J].Advanced Energy Materials,2014,4(12):1.
-
[13]
XIAO X L,WU G Z,ZHOU H T,et al.Preparation and property evaluation of conductive hydrogel using poly (vinyl alcohol)/polyethylene glycol/graphene oxide for human electrocardiogram acquisition[J].Polymers,2017,9(7):1.
-
[14]
POLAT T G,ATES K,BILGIN S,et al.Carbon nanotube,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) and Ag nanoparticle doped gelatin based electro-active hydrogel systems[J].Colloids and Surfaces A(Physicochemical and Engineering Aspects),2019,580:123.
-
[15]
WANG S P,SUN C K,GUAN S,et al.Chitosan/gelatin porous scaffolds assembled with conductive poly(3,4-ethylenedioxythiophene) nanoparticles for neural tissue engineering[J].Journal of Materials Chemistry B,2017(24):4774.
-
[16]
KAI R,YU C,CHAO H,et al.Self-healing conductive hydrogels based on alginate,gelatin and polypyrrole serve as a repairable circuit and a mechanical sensor[J].Journal of Materials Chemistry B,2019,7(37):5704.
-
[17]
WIECZOREK W,STEVENS J R.Proton transport in polyacrylamide based hydrogels doped with H3PO4 or H2SO4[J].Polymer,1997,38(9):2057.
-
[18]
PRZYŁUSKI J,POŁTARZEWSKI Z,WIECZOREK W.Proton-conducting hydrogel membranes[J].Polymer,1998,39(18):4343.
-
[19]
丁丹,王晶,陈莹,等.明胶-聚丙烯酸纳米微球的一维自组装制备纳米棒[J].中国科学(化学),2011,41(2):374.
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