基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

刘瑞雪; 陈纪超; 李迎博

doi:10.12187/2021.06.013

基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

郑州轻工业大学材料与化学工程学院, 河南郑州 450001

作者简介: 刘瑞雪(1971-),女,河南省范县人,郑州轻工业大学副教授,博士,主要研究方向为高分子水凝胶、功能高分子材料.;

基金项目: 国家自然科学基金项目（21474092）；河南省留学归国人员择优资助项目（002422）
中图分类号: O63

Research progress of self-healing hydrogels based on dynamic covalent bond and non-covalent bond interaction

College of Materials and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China
Received Date: 2020-08-01
Accepted Date: 2021-02-15

CLC number: O63

摘要: 综述了基于动态共价键、非共价键相互作用的自愈合水凝胶及其在伤口敷料和药物输送、组织工程、仿生电子皮肤、可穿戴电子设备方面的应用，对常用自愈合水凝胶的自愈机制进行概述，针对目前单一的基于动态共价键或动态非共价键相互作用机制的自愈合水凝胶仍然存在力学性能弱、自愈条件苛刻、不能完全恢复等不足，指出了未来自愈合水凝胶的设计研究方向：如可在多种环境下发生自愈行为的自愈合水凝胶的设计、动态共价/非共价相互作用结合的自愈合水凝胶的设计、自愈合水凝胶用于柔性电子器件等方面的研究等，以实现多机制、多功能型自愈合水凝胶的快速发展，促进其在生物材料、智能软材料方面应用的有效拓展.
- 自愈合水凝胶 /
- 动态共价键 /
- 动态非共价键 /
- 生物医药 /
- 电子传感
Abstract: Self-healing hydrogels based on dynamic covalent bonds or noncovalent interactions and their applications in wound dressing, drug delivery, tissue engineering, bionic electronic skin and wearable electronic devices were reviewed in this paper. The commonly used self-healing mechanisms for preparing self-healing hydrogels were represented in detail. At the same time, as self-healing hydrogels under solo dynamic covalent bonds or noncovalent interaction mechanisms had some shortcoming, such as weak mechanical properties, rigor self-healing conditions, incomplete recovery, and so on, the research direction of designing of self-healing hydrogels in the future was pointed out such as, design of self-healing hydrogels with self-healing behavior in various environments,self-healing hydrogels combined with dynamic covalent/non-covalent interactions,selfhealing hydrogels for flexible electronic devices,and so on, which aimed to achieve the rapid development of multi-mechanism and multi-functional self-healing hydrogels, and promote its effective application in biomaterials and soft intelligent materials.
- self-healing hydrogel /
- dynamic covalent bond /
- dynamic non-covalent bond /
- biomedicine /
- electronic sensor
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沈阳化工大学材料科学与工程学院沈阳 110142

基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

作者简介: 刘瑞雪(1971-),女,河南省范县人,郑州轻工业大学副教授,博士,主要研究方向为高分子水凝胶、功能高分子材料.;

Research progress of self-healing hydrogels based on dynamic covalent bond and non-covalent bond interaction

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通讯作者: 陈斌, bchen63@163.com

基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

作者简介:刘瑞雪(1971-),女,河南省范县人,郑州轻工业大学副教授,博士,主要研究方向为高分子水凝胶、功能高分子材料.

English Abstract

Research progress of self-healing hydrogels based on dynamic covalent bond and non-covalent bond interaction

目录

基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

作者简介: 刘瑞雪(1971-),女,河南省范县人,郑州轻工业大学副教授,博士,主要研究方向为高分子水凝胶、功能高分子材料.;

Research progress of self-healing hydrogels based on dynamic covalent bond and non-covalent bond interaction

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通讯作者: 陈斌, bchen63@163.com

基于动态共价键和非共价键相互作用的自愈合水凝胶研究进展

作者简介:刘瑞雪(1971-),女,河南省范县人,郑州轻工业大学副教授,博士,主要研究方向为高分子水凝胶、功能高分子材料.

English Abstract

Research progress of self-healing hydrogels based on dynamic covalent bond and non-covalent bond interaction

目录