金属催化腈水解反应制备伯酰胺衍生物的研究进展

徐粉; 康位粉; 孟彦羽; 张立朝; 方少明

doi:10.3969/j.issn.2096-1553.2017.1.011

金属催化腈水解反应制备伯酰胺衍生物的研究进展

郑州轻工业学院材料与化学工程学院, 河南郑州 450001;
河南农业大学理学院, 河南郑州 450002

通讯作者: 方少明

基金项目: 河南省高等学校重点项目（17A150053）；郑州轻工业学院博士基金项目（2014BSJJ017）
中图分类号: O621.3;O626.32

Research progress of hydrdysis reaction of nitriles to form amide derivatives catalyzed by metal catalyst

College of Material and Chemical Engineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China;
College of Science, He'nan Agricultural University, Zhengzhou 450002, China

Corresponding author: FANG Shao-ming,

Received Date: 2016-01-05
Available Online: 2017-01-15
CLC number: O621.3;O626.32

摘要: 鉴于金属催化腈水解制备伯酰胺衍生物的反应表现出高原子经济性、高选择性，对Mo系金属催化剂、Ru系金属催化剂、Rh系金属催化剂、Pd系金属催化剂、Au/Ag系金属催化剂等不同类型金属催化剂催化腈水解反应制备伯酰胺衍生物的研究进展进行了综述.提出，对腈水解反应制备伯酰胺衍生物的研究仍存在巨大的挑战，如非均相Ru系金属催化体系和选择性专一的伯酰胺催化剂体系的研发、均相和非均相催化体系反应机理的实验验证、将水作为唯一溶剂的研究等，都是未来的发展方向.
- 金属催化剂 /
- 腈水解反应 /
- 伯酰胺衍生物
Abstract: Considering the high atom economy and selectivity towards hydrolysis reaction derivatives of nitriles to form amides, progress in recent years for this transformation catalyzed by different metal catalysts was reviewed such as a variety of catalysts composed of transition-metal complexes such as Mo, Ru, Rh, Pd and Au/Ag. Specially, Ru-metal catalysts was exploited deeply and draw more attention of science researcher. However, hydrolysis reaction derivatives of nitriles to form amides catalyzed by metal catalysts remains a formidable challenge, including the development of heterogeneous Ru-metal catalysts and high selectivity catalysts, bringing insight into the mechanism of homogeneous and heterogeneous catalytic reaction, seeking for new system with pure water as solvent.
- metal catalyst /
- hydrdysis reaction of nitriles /
- amide derivative
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沈阳化工大学材料科学与工程学院沈阳 110142

金属催化腈水解反应制备伯酰胺衍生物的研究进展

通讯作者: 方少明

Research progress of hydrdysis reaction of nitriles to form amide derivatives catalyzed by metal catalyst

Corresponding author: FANG Shao-ming,

计量

通讯作者: 陈斌, bchen63@163.com

金属催化腈水解反应制备伯酰胺衍生物的研究进展

通讯作者: 方少明

English Abstract

Research progress of hydrdysis reaction of nitriles to form amide derivatives catalyzed by metal catalyst

Corresponding author: FANG Shao-ming,

目录

金属催化腈水解反应制备伯酰胺衍生物的研究进展

通讯作者: 方少明

Research progress of hydrdysis reaction of nitriles to form amide derivatives catalyzed by metal catalyst

Corresponding author: FANG Shao-ming,

计量

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通讯作者: 陈斌, bchen63@163.com

金属催化腈水解反应制备伯酰胺衍生物的研究进展

通讯作者: 方少明

English Abstract

Research progress of hydrdysis reaction of nitriles to form amide derivatives catalyzed by metal catalyst

Corresponding author: FANG Shao-ming,

目录