动物源性食品兽药多残留检测中基质净化与液相色谱-质谱联用技术研究进展

季宝成; 杨澜瑞; 韩雨; 白艳红; 许旭

doi:10.12187/2023.05.002

October 2023

Article Contents

JI Baocheng, YANG Lanrui, HAN Yu, et al. Research progress on matrix purification combined with LC-MS method for the detection of veterinary drug residues in animal-derived foods[J]. Journal of Light Industry, 2023, 38(5): 8-16. doi: 10.12187/2023.05.002

Citation: JI Baocheng, YANG Lanrui, HAN Yu, et al. Research progress on matrix purification combined with LC-MS method for the detection of veterinary drug residues in animal-derived foods[J]. Journal of Light Industry, 2023, 38(5): 8-16. doi: 10.12187/2023.05.002 shu

Research progress on matrix purification combined with LC-MS method for the detection of veterinary drug residues in animal-derived foods

JI Baocheng ^1,2,3 ,
YANG Lanrui ^1,2,3 ,
HAN Yu ^1,2,3 ,
BAI Yanhong ^1,2,3 ,
XU Xu ^1,2,3

1. College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China;
2. Henan Key Laboratory of Cold Chain Food Safety Quality and Safety Control, Zhengzhou 450001, China;
3. Henan Collaborative Innovation Center for Food production and Safety, Zhengzhou 450001, China

Received Date: 2022-08-29
Accepted Date: 2022-10-26

Abstract

The research progress in matrix purification combined with liquid chromatography-mass spectrometry (LC-MS) method as well as their applications in determination of veterinary drugs in animal-derived foods was reviewed. Among various matrix purification methods, liquid liquid extraction (LLE), dispersed liquid liquid microextraction (DLLME), solid phase extraction (SPE), solid phase microextraction (SPME), dispersed solid phase extraction (DSPE), and magnetic solid phase extraction (MSPE) are mostly widely used in different animal derived foods such as meat, eggs, milk, and their products. However, there are still some limitations, such as weak matrix selectivity of LLE, limited applicability of DLLME, moderate purification efficiency DPSE, poor reproducibility of SPME, and time-consuming operation of SPE. In the future, the detection technology of veterinary drugs in various animal-derived foods could be further studied in terms of establishing simultaneous purification methods for various kinds of veterinary drugs, developing novel and efficient matrix-based purification materials, and enhancing convenience and automation in matrix purification process to meet the urgent needs in screening of multi-residues of veterinary drugs in animal-derived foods.
- animal-derived food,
- veterinary drug residues,
- LC-MS,
- matrix purification technology
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沈阳化工大学材料科学与工程学院沈阳 110142

Research progress on matrix purification combined with LC-MS method for the detection of veterinary drug residues in animal-derived foods

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