JOURNAL OF LIGHT INDUSTRY

CN 41-1437/TS  ISSN 2096-1553

Volume 31 Issue 4
July 2016
Article Contents
WU Ci, LIANG Yu, LIANG Zhen, et al. Preparation of monolithic materials and applications in proteomic chromatographic separation[J]. Journal of Light Industry, 2016, 31(4): 1-14. doi: 10.3969/j.issn.2096-1553.2016.4.001
Citation: WU Ci, LIANG Yu, LIANG Zhen, et al. Preparation of monolithic materials and applications in proteomic chromatographic separation[J]. Journal of Light Industry, 2016, 31(4): 1-14. doi: 10.3969/j.issn.2096-1553.2016.4.001 shu

Preparation of monolithic materials and applications in proteomic chromatographic separation

  • Received Date: 2016-04-13
  • With the advantages of facile preparation,fast mass transfer,low backpressure and easy modification,monolithic materials have been widely used in chromatographic separation.In order to familiarize professionals of home and abroad with the present situation of monolithic materials,this review mainly summarizes the preparation methods of different kinds of monolithic materials (including organic polymer monoliths,silica-based monoliths,organic-inorganic hybrid silica monoliths) and their applications in the separation of proteins or peptides in proteomics.It was pointed out that compared with packed column, monolithic packed column efficiency was to be further improved from the performance of monolithic materials, such as specific surface area, pore size distribution, stablity and hydrophilicity.Taking advantage of the love backpressure of monolithic materials, the caoillary monolithic column with superlong and superfine inner diameter was prepared in order to make high efficient separation analysis of macro proteomics samples. With the further study of monolithic materials preparation technology, monolithic materials will play more important role in the fields of food safety, life science and environment.
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    1. [1]

      HJERTEN S,LIAO J L,ZHANG R.High-performanceliquid chromatography on continuous polymer beds[J].Journal of Chromatography A,1989,473:273.

    2. [2]

      TANAKA N,MCCALLEY D V.Core-shell,ultrasmall particles,monoliths,and other support materials in high-performance liquid chromatography[J].Analytical Chemistry,2016,88(1):279.

    3. [3]

      WU R A,HU L,WANG F,et al.Recent deve-lopment of monolithic stationary phases with emphasis on microscale chromatographic separation[J].Journal of Chromatography A,2008,1184(1):369.

    4. [4]

      SVEC F,LV Y.Advances and recent trends in the field of monolithic columns for chromatography[J].Analytical Chemistry,2014,87(1):250.

    5. [5]

      PETERS E C,SVEC F,FRECHET J M.Rigid macroporous polymer monoliths[J].Advanced Materials,1999,11(14):1169.

    6. [6]

      ARRUA R D,TALEBI M,CAUSON T J,et al.Review of recent advances in the preparation of organic polymer monoliths for liquid chromatography of large molecules[J].Analytica Chimica Acta,2012,738:1.

    7. [7]

      NISCHANG I.Porous polymer monoliths:morphology,porous properties,polymer nanoscale gel structure and their impact on chromatographic performance[J].Journal of Chromatography A,2013,1287:39.

    8. [8]

      YU S,NG F L,MA K C C,et al.Effect of porogenic solvent on the porous properties of polymer monoliths[J].Journal of Applied Polymer Science,2013,127(4):2641.

    9. [9]

      SVEC F,FRECHET J M J.Continuous rods of macroporous polymer as high-performance liquid chromatography separation media[J].Analytical Chemistry,1992,64(7):820.

    10. [10]

      PETERS E C,PETRO M,SVEC F,et al.Molded rigid polymer monoliths as separation media for capillary electrochromatography.2.Effect of chromatographic conditions on the separation[J].Analytical Chemistry,1998,70(11):2296.

    11. [11]

      LE T P,MOAD G,RIZZARDO E,et al.Polymerization with living characteristics:US 7250479[P].2007-07-31.

    12. [12]

      IDE N,FUKUDA T.Nitroxide-controlled free-radical copolymerization of vinyl and divinyl monomers.2.Gelation[J].Macromolecules,1999,32(1):95.

    13. [13]

      CHEN Z,YE Q.Doping a novel controlled/"living" radical for the polymerization of a lauryl methacrylate monolithic column for improving column efficiency[J].Analytical Methods,2014,6(10):3235.

    14. [14]

      LUBBAD S H,BUCHMEISER M R.Ring-opening metathesis polymerization-derived monolithic anion exchangers for the fast separation of double-stranded DNA fragments[J].Journal of Chromatography A,2011,1218(17):2362.

    15. [15]

      LUBBAD S H,BANDARI R,BUCHMEISER M R.Ring-opening metathesis polymerization-derived monolithic strong anion exchangers for the separation of 5'-phosphorylated oligodeoxythymidylic acids fragments[J].Journal of Chromatography A,2011,1218(49):8897.

    16. [16]

      LIU Z,OU J,LIN H,et al.Preparation of monolithic polymer columns with homogeneous structure via photoinitiated thiol-yne click polymerization and their application in separation of small molecules[J].Analytical Chemistry,2014,86(24):12334.

    17. [17]

      LIN H,OU J,LIU Z,et al.Thiol-epoxy click polymerization for preparation of polymeric monoliths with well-defined 3D framework for capillary liquid chromatography[J].Analytical Chemistry,2015,87(6):3476.

    18. [18]

      LV Y,LIN Z,SVEC F.Hypercrosslinked large surface area porous polymer monoliths for hydrophilic interaction liquid chromatography of small molecules featuring zwitterionic functionalities attached to gold nanoparticles held in layered structure[J].Analytical Chemistry,2012,84(20):8457.

    19. [19]

      URBAN J,SVEC F,FRECHET J M J.Efficient separation of small molecules using a large surface area hypercrosslinked monolithic polymer capillary column[J].Analytical Chemistry,2010,82(5):1621.

    20. [20]

      URBAN J,SVEC F,FRECHET J M J.Hypercrosslinking:new approach to porous polymer monolithic capillary columns with large surface area for the highly efficient separation of small molecules[J].Journal of Chromatography A,2010,1217(52):8212.

    21. [21]

      XU Y,CAO Q,SVEC F,et al.Porous polymer monolithic column with surface-bound gold nanoparticles for the capture and separation of cysteine-containing peptides[J].Analytical Chemistry,2010,82(8):3352.

    22. [22]

      CHAMBERS S D,HOLCOMBE T W,SVEC F,et al.Porous polymer monoliths functionalized through copolymerization of a C60 fullerene-containing methacrylate monomer for highly efficient separations of small molecules[J].Analytical Chemistry,2011,83(24):9478.

    23. [23]

      KRENKOVA J,LACHER N A,SVEC F.Control of selectivity via nanochemistry:monolithic capillary column containing hydroxyapatite nanoparticles for separation of proteins and enrichment of phosphopeptides[J].Analytical Chemistry,2010,82(19):8335.

    24. [24]

      TONG S,LIU S,WANG H,et al.Recent advances of polymer monolithic columns functionalized with micro/nanomaterials:synthesis and application[J].Chromatographia,2014,77(1/2):5.

    25. [25]

      JANDERA P,URBAN J,ŠKEŘKOV V,et al.Polymethacrylate monolithic and hybrid particle-monolithic columns for reversed-phase and hydrophilic interaction capillary liquid chromatography[J].Journal of Chromatography A,2010,1217(1):22.

    26. [26]

      WANG M M,YAN X P.Fabrication of graphene oxide nanosheets incorporated monolithic column via one-step room temperature polymerization for capillary electrochromatography[J].Analytical Chemistry,2011,84(1):39.

    27. [27]

      FU Y Y,YANG C X,YAN X P.Incorporation of metal-organic framework UiO-66 into porous polymer monoliths to enhance the liquid chromatographic separation of small molecules[J].Chemical Communications,2013,49(64):7162.

    28. [28]

      SEO M,KIM S,OH J,et al.Hierarchically porous polymers from hyper-cross-linked block polymer precursors[J].Journal of the American Chemical Society,2015,137(2):600.

    29. [29]

      SABA S A,MOUSAVI M P,BVHLMANN P,et al.Hierarchically porous polymer monoliths by combining controlled macro-and microphase separation[J].Journal of the American Chemical Society,2015,137(28):8896.

    30. [30]

      MINAKUCHI H,NAKANISHI K,SOGA N,et al.Octadecylsilylated porous silica rods as separation media for reversed-phase liquid chromatography[J].Analytical Chemistry,1996,68(19):3498.

    31. [31]

      SMÅTT J,SCHUNK S,LINDEN M.Versatile double-templating synthesis route to silica monoliths exhibiting a multimodal hierarchical porosity[J].Chemistry of Materials,2003,15(12):2354.

    32. [32]

      ZHONG H,LIU J,WANG P,et al.Inorganic salt aided synthesis of monolithic silica with meso/macro hierarchical structure[J].Microporous and Mesoporous Materials,2009,123(1):63.

    33. [33]

      AMATANI T,NAKANISHI K,HIRAO K,et al.Monolithic periodic mesoporous silica with well-defined macropores[J].Chemistry of Materials,2005,17(8):2114.

    34. [34]

      BABIN J,IAPICHELLA J,LEFEVRE B,et al.MCM-41 silica monoliths with independent control of meso-and macroporosity[J].New Journal of Chemistry,2007,31(11):1907.

    35. [35]

      ZHONG H,ZHU G,WANG P,et al.Direct synthesis of hierarchical monolithic silica for high performance liquid chromatography[J].Journal of Chromatography A,2008,1190(1):232.

    36. [36]

      BIDEAU J L,MIAH M Y,VIOUX A,et al.Bimodal porous silica monoliths obtained by phase separation in non-aqueous media[J].Journal of Materials Chemistry,2010,20(5):964.

    37. [37]

      DRISKO G L,ZELCER A,CARUSO R A,et al.One-pot synthesis of silica monoliths with hierarchically porous structure[J].Microporous and Mesoporous Materials,2012,148(1):137.

    38. [38]

      GUO J,LU Y,ZHANG S.Preparation of a high specific surface area monolithic silica reversed phase chromatography column using a template induced method[J].New Journal of Chemistry,2014,38(9):4190.

    39. [39]

      WANG K,CHEN Y,YANG H,et al.Modification of VTMS hybrid monolith via thiol-ene click chemistry for capillary electrochromatography[J].Talanta,2012,91:52.

    40. [40]

      FENG R,TIAN Y,CHEN H,et al.Terminal-vinyl liquid crystal crown ether-modified,vinyl-functionalized hybrid silica monolith for capillary electrochromatography[J].Electrophoresis,2010,31(12):1975.

    41. [41]

      XU L,LEE H K.Preparation,characterization and analytical application of a hybrid organic-inorganic silica-based monolith[J].Journal of Chromatography A,2008,1195(1):78.

    42. [42]

      COL N H,ZHANG X,MURPHY J K,et al.Allyl-functionalized hybrid silica monoliths[J].Chemical Communications,2005(22):2826.

    43. [43]

      YAN L,ZHANG Q,ZHANG J,et al.Hybrid organic-inorganic monolithic stationary phase for acidic compounds separation by capillary electrochromatography[J].Journal of Chromatography A,2004,1046(1):255.

    44. [44]

      MA J,LIANG Z,QIAO X,et al.Organic-inorganic hybrid silica monolith based immobilized trypsin reactor with high enzymatic activity[J].Analytical Chemistry,2008,80(8):2949.

    45. [45]

      HOU C,MA J,TAO D,et al.Organic-inorganic hybrid silica monolith based immobilized titanium ion affinity chromatography column for analysis of mitochondrial phosphoproteome[J].Journal of Proteome Research,2010,9(8):4093.

    46. [46]

      DENG N,LIANG Z,LIANG Y,et al.Aptamer modified organic-inorganic hybrid silica monolithic capillary columns for highly selective recognition of thrombin[J].Analytical Cemistry,2012,84(23):10186.

    47. [47]

      WU M,WU RA,WANG F,et al. "One-pot" process for fabrication of organic-silica hybrid monolithic capillary columns using organic monomer and alkoxysilane[J].Analytical Chemistry,2009,81(9):3529.

    48. [48]

      ZHANG Z,WANG F,XU B,et al.Preparation of capillary hybrid monolithic column with sulfonate strong cation exchanger for proteome analysis[J].Journal of Chromatography A,2012,1256:136.

    49. [49]

      ZHANG Z,WU M,WU RA,et al.Preparation of perphenylcarbamoylated β-cyclodextrin-silica hybrid monolithic column with "one-pot" approach for enantioseparation by capillary liquid chromatography[J].Analytical Chemistry,2011,83(9):3616.

    50. [50]

      ZHANG Z,WANG F,OU J,et al.Preparation of a butyl-silica hybrid monolithic column with a "one-pot" process for bioseparation by capillary liquid chromatography[J].Analytical and Bioanalytical Chemistry,2013,405(7):2265.

    51. [51]

      ZHANG Z,LIN H,OU J,et al.Preparation of phenyl-silica hybrid monolithic column with "one-pot" process for capillary liquid chromatography[J].Journal of Chromatography A,2012,1228:263.

    52. [52]

      ZHANG Z,WANG F,DONG J,et al.A "one step" approach for preparation of an octadecyl-silica hybrid monolithic column via a non-hydrolytic sol-gel (NHSG) method[J].RSC Advances,2013,3:8.

    53. [53]

      MARK J E.Some interesting things about polysiloxanes[J].Accounts of Chemical Research,2004,37(12):946.

    54. [54]

      TANAKA K,CHUJO Y.Advanced functional materials based on polyhedral oligomeric silsesquioxane (POSS)[J].Journal of Materials Chemistry,2012,22(5):1733.

    55. [55]

      LIN H,CHEN L,OU J,et al.Preparation of well-controlled three-dimensional skeletal hybrid monoliths via thiol-epoxy click polymerization for highly efficient separation of small molecules in capillary liquid chromatography[J].Journal of Chromatography A,2015,1416:74.

    56. [56]

      LIN H,OU J,LIU Z,WANG H,et al.Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography[J].Journal of Chromatography A,2015,1379:34.

    57. [57]

      ZHANG H,OU J,LIU Z,et al.Preparation of hybrid monolithic columns via "one-pot" photoinitiated thiol-acrylate polymerization for retention-independent performance in capillary liquid chromatography[J].Analytical Chemistry,2015,87(17):8789.

    58. [58]

      LIU Z,OU J,LIN H,et al.Preparation of polyhedral oligomeric silsesquioxane-based hybrid monolith by ring-opening polymerization and post-functionalization via thiol-ene click reaction[J].Journal of Chromatography A,2014,1342:70.

    59. [59]

      INAGAKI S,GUAN S,FUKUSHIMA Y,et al.Novel mesoporous materials with a uniform distribution of organic groups and inorganic oxide in their frameworks[J].Journal of the American Chemical Society,1999,121(41):9611.

    60. [60]

      SALESCH T,BACHMANN S,BRUGGER S,et al.New inorganic-organic hybrid materials for HPLC separation obtained by direct synthesis in the presence of a surfactant[J].Advanced Functional Materials,2002,12(2):134.

    61. [61]

      REBBIN V,SCHMIDT R,FROBA M.Spherical particles of phenylene-bridged periodic mesoporous organosilica for high-performance liquid chromatography[J].Angewandte Chemie International Edition,2006,45(31):5210.

    62. [62]

      NAKANISHI K,KOBAYASHI Y,AMATANI T,et al.Spontaneous formation of hierarchical macro-mesoporous ethane-silica monolith[J].Chemistry of Materials,2004,16(19):3652.

    63. [63]

      BRANDHUBER D,PETERLIK H,HUESING N.Facile self-assembly processes to phenylene-bridged silica monoliths with four levels of hierarchy[J].Small,2006,2(4):503.

    64. [64]

      ZHONG H,ZHU G,YANG J,et al.Periodic mesoporous hybrid monolith with hierarchical macro-mesopores[J].Microporous and Mesoporous Materials,2007,100(1):259.

    65. [65]

      CAUSON T J,NISCHANG I.Critical differences in chromatographic properties of silica-and polymer-based monoliths[J].Journal of Chromatography A,2014,1358:165.

    66. [66]

      BAI L,WANG J,ZHANG H,et al.Ionic liquid as porogen in the preparation of a polymer-based monolith for the separation of protein by high performance liquid chromatography[J].Analytical Methods,2015,7(2):607.

    67. [67]

      MASINI J C.Separation of proteins by cation-exchange sequential injection chromatography using a polymeric monolithic column[J].Analytical and Bioanalytical Chemistry,2016,408(5):1445.

    68. [68]

      SIMONE P,PIERRI G,FOGLIA P,et al.Separation of intact proteins on γ-ray-induced polymethacrylate monolithic columns:a highly permeable stationary phase with high peak capacity for capillary high-performance liquid chromatography with high-resolution mass spectrometry[J].Journal of Separation Science,2015,39(2):1.

    69. [69]

      LIU Z,OU J,LIU Z,et al.Separation of intact proteins by using polyhedral oligomeric silsesquioxane based hybrid monolithic capillary columns[J].Journal of Chromatography A,2013,1317:138.

    70. [70]

      NISCHANG I,SVEC F,FRECHET J M.Downscaling limits and confinement effects in the miniaturization of porous polymer monoliths in narrow bore capillaries[J].Analytical Chemistry,2009,81(17):7390.

    71. [71]

      JIANG X,DONG J,WANG F,et al.Automation of nanoflow liquid chromatography-tandem mass spectrometry for proteome and peptide profiling analysis by using a monolithic analytical capillary column[J].Electrophoresis,2008,29(8):1612.

    72. [72]

      MEENT M H M V D,EELTINK S,JONG G D J.Potential of poly (styrene-co-divinylbenzene) monolithic columns for the LC-MS analysis of protein digests[J].Analytical and Bioanalytical Chemistry,2011,399(5):1845.

    73. [73]

      EELTINK S,DOLMAN S,DETOBEL F,et al.High-efficiency liquid chromatography-mass spectrometry separations with 50 mm,250 mm,and 1 m long polymer-based monolithic capillary columns for the characterization of complex proteolytic digests[J].Journal of Chromatography A,2010,1217(43):6610.

    74. [74]

      HORIE K,KAMAKURA T,IKEGAMI T,et al.Hydrophilic interaction chromatography using a meter-scale monolithic silica capillary column for proteomics LC-MS[J].Analytical Chemistry,2014,86(8):3817.

    75. [75]

      CHEN X,TOLLEY H D,LEE M L.Monolithic capillary columns synthesized from a single phosphate-containing dimethacrylate monomer for cation-exchange chromatography of peptides and proteins[J].Journal of Chromatography A,2011,1218(28):4322.

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