LIU You-ting and LIU Yu-hong. Study on whitening efficacy of rhodiola crenulata extract on the biochemistry and cell level[J]. Journal of Light Industry, 2016, 31(4): 39-43. doi: 10.3969/j.issn.2096-1553.2016.4.005
Citation:
LIU You-ting and LIU Yu-hong. Study on whitening efficacy of rhodiola crenulata extract on the biochemistry and cell level[J]. Journal of Light Industry, 2016, 31(4): 39-43.
doi:
10.3969/j.issn.2096-1553.2016.4.005
Study on whitening efficacy of rhodiola crenulata extract on the biochemistry and cell level
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Chinese Cosmetic Collaborative Innovation Center, Beijing Technology and Business University, Beijing 100048, China
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Received Date:
2016-04-13
Available Online:
2016-07-15
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Abstract
The rhodiola crenulata extract was prepared by the method of ultrasonic extraction, and the quality concentration of the extract was 0.05 g/mL.The experiments of clearance rate of DPPH free radical and inhibition rate of tyrosinase were conducted to evaluate the whitening efficacy of biochemistry level of the rhodiola crenulata extract, and the test of mouse B16 melanoma cell was applied to evaluate the whitening efficacy of cell level.The results showed that under the concentration of 1.0 wt%, the clearance rate of DPPH was 92.2%, the inhibition rate of tyrosinase was 79.1%,melanoma cell comparative survival rate was up to 75%, and the inhibition rate of melanin synthesis to mouse B16 melanoma cell was 39.0%.It declared that the prepared rhodiola crenulata extract had good function of clearing DPPH free radical and inhibiting tyrosinase.Therefore, the rhodiola crenulata extract has excellent whitening efficacy on the biochemistry and cell level, which had a good potential to apply into the whitening cosmetics.
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