JOURNAL OF LIGHT INDUSTRY

CN 41-1437/TS  ISSN 2096-1553

Volume 34 Issue 3
May 2019
Article Contents
WANG Jun, LI Yingbin, YANG Xuzhao, et al. Study on the interaction between imidazolium-based ionic liquid surfactant and bovine serum albumin mixed system[J]. Journal of Light Industry, 2019, 34(3): 21-27. doi: 10.3969/j.issn.2096-1553.2019.03.002
Citation: WANG Jun, LI Yingbin, YANG Xuzhao, et al. Study on the interaction between imidazolium-based ionic liquid surfactant and bovine serum albumin mixed system[J]. Journal of Light Industry, 2019, 34(3): 21-27. doi: 10.3969/j.issn.2096-1553.2019.03.002 shu

Study on the interaction between imidazolium-based ionic liquid surfactant and bovine serum albumin mixed system

  • Received Date: 2019-02-20
  • 1-N-tetradecyl-3-methylimidazolium dicyanamide salt ([C14mim] [DCA] was synthesized by two-step method using N-methylimidazole, bromotetradecane and dicyandiamide silver as raw materials. The structure of the product was characterized and the interaction of[C14mim] [DCA] with bovine serum albumin (BSA) was studied. The results showed that 1) The cmc value and Amin value of the mixed system increased with the increase of BSA concentration; 2) The interaction between[C14mim] [DCA] and BSA in the mixed system had an effect on the microenvironment of amino acid residues on BSA, and main influenced the tryptophan (Trp) residue on BSA; 3) The interaction between[C14mim] [DCA] and BSA in the mixed system affectd the hydraulic radius of the system, and with the increase of[C14mim] [DCA] concentration, the hydraulic radius of the[C14mim] [DCA]/BSA system became larger and had an effect on the structure of the BSA——BSA was unfolded.
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